YHS-12 is an ionizable lipid used to create lipid nanoparticles for RNA delivery. LNPs with a 15:10:25:2.5 (YHS-12/DOPE/cholesterol/DMG-PEG) formula efficiently deliver mRNA and siRNA to Raw264.7-Luc cells, targeting monocytes in vivo to enhance MRSA-targeted CAR mRNA and CASP11 siRNA delivery.
PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Branched Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Branched Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Multi chargeable lipid | Products > Lipids In Drug Delivery > Branched Lipid > Branched Lipid
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