PT-65 functions as a robust GSK3 Degrader utilizing the PROTAC mechanism. Demonstrating significant activity against GSK3α and GSK3β, it effectively mitigates Okadaic acid-induced tau hyperphosphorylation. Additionally, PT-65 showcases the ability to improve learning and memory deficits in rat models of Alzheimer's disease. Reagent-grade; for laboratory research purposes only.
Products > PROTAC, Molecular glue > Degraders
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