NI 57

Overview

NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI 57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI 57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts. Please contact us for GMP-grade inquiries.

Application

Products > PROTAC, Molecular glue > Inhibitors

Product Information

• Catalog No.: BP-25365
• CAS No.: 1883548-89-7
• Molecular Formula: C19H17N3O4S
• Molecular Weight: 383.4
• Storage: -20°C
• Availability: In Stock

Source

Original product source