FTT5 LLNs (solution in ethanol)

Overview

FTT5 is a lipid-like compound derived from the ionizable cationic amino lipid TT3 and has been utilized in the creation of lipid-like nanoparticles (LLNs). LLNs incorporating FTT5 and an mRNA reporter enhance luminescence in Hep3B cells and preferentially accumulate in the liver of mice. Additionally, LLNs with FTT5 and mRNA encoding human Factor VIII increase plasma Factor VIII activity in a hemophilia A mouse model. FTT5-containing LLNs have also been employed for genome editing in mice.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Branched Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Branched Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Multi chargeable lipid | Products > Lipids In Drug Delivery > Branched Lipid > Branched Lipid

Product Information

• Catalog No.: BP-42674
• CAS No.: 2803606-43-9
• Molecular Formula: C120H222N6O15
• Molecular Weight: 1989.1
• Storage: -20°C
• Availability: In Stock

Source

Original product source