CRBN-6-5-5-VHL

Overview

CRBN-6-5-5-VHL is a selective degrader that utilizes the von Hippel-Lindau (VHL) system to target cereblon (CRBN). This compound demonstrates a strong potency for degradation while exhibiting minimal impact on the neo-substrates IKZF1 and IKZF3. Its structural design focuses on optimizing the interactions with the E3 ligase complex to enhance degradation efficiency. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42231
• CAS No.: 2362575-45-7
• Molecular Formula: C51H69N7O10S
• Molecular Weight: 972.2
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source