Inosine-5'-diphosphate disodium

Overview

Inosine-5'-diphosphate disodium (IDP disodium) is a decoy substrate of NM23-H2 . Inosine-5'-diphosphate disodium has a superior bond capacity on GDP-binding pocket of NM23-H2 ( K D : 5.0 μM). Inosine-5'-diphosphate disodium abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate disodium has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate disodium can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research.

Application

Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleotides | Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleotides > Diphosphate

Product Information

• Catalog No.: BP-43602
• CAS No.: 54735-61-4
• Molecular Formula: C10H12N4Na2O11P2
• Molecular Weight: 472.2
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source