MC-Val-Cit-PAB-MMAF

Overview

MC-Val-Cit-PAB-MMAF is a precursor of antibody drug conjugates (ADCs) with an enzymatically cleavable VAl-Cit site. The maleimide group is reactive with thiol bearing molecules. MMAF is a synthetic antineoplastic agent which may be employed as a cytotoxic payload. The Val-Cit will specifically be cleaved by Cathepsin B.

Application

Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Cit-MMAF | Products > ADC Linker, ADC Payload > ADC Payload > MMAF

Product Information

• Catalog No.: BP-27843
• CAS No.: 863971-17-9
• Molecular Formula: C68H103N11O16
• Molecular Weight: 1330.6
• Storage: -20°C
• Solubility: DMSO, DMF
• Availability: In Stock

Source

Original product source