Idasanutlin is a potent MDM2 inhibitor with an IC50 = 6 nM in binding assay and 30 nM in cancer cell proliferation assay. It induces p53 stabilisation, cell cycle arrest and apoptosis. It displays inhibition of tumor growth in the SJSA1 tumor xenograft model and also inhibits MDR-1 at high concentrations. Please contact us for GMP-grade inquiries.
Products > PROTAC, Molecular glue > Inhibitors
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