Fmoc-Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide

Overview

Fmoc-Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide (also known as "Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH") is a Fmoc protected protease-cleavable linker featuring the GGFG (Gly-Gly-Phe-Gly) sequence. It can be used in the synthesis of antibody-drug conjugates (ADCs) by attaching to payloads and antibodies. The Fmoc group can be removed under basic conditions to yield a free amine for further conjugation.

Application

Products > ADC Linker, ADC Payload > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Gly-Gly-Phe-Gly (GGFG)

Product Information

• Catalog No.: BP-29528
• CAS No.: 2264011-98-3
• Molecular Formula: C33H35N5O9
• Molecular Weight: 645.7
• Storage: -20°C
• Availability: In Stock

Source

Original product source