Boc-Val-Ala-PAB-PNB is a cleavable peptide ADC linker. The Val-Ala will specifically be cleaved by Cathepsin B. Since this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. PNP can be substituted by amine-bearing molecules.
Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Ala
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