KB02-JQ1 is a selective PROTAC-based degrader specifically targeting BRD4 while sparing BRD2 and BRD3. Its mechanism involves covalent modification of DCAF16, an E3 ligase, which enhances the stability of protein degradation within biological contexts. The compound comprises a linker connecting the JQ1 ligand to the ubiquitin E3 ligase ligand KB02, facilitating its function as a molecular glue. Reagent-grade; for laboratory research purposes only.
Products > PROTAC, Molecular glue > Degraders
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