Silymarin is an extract of the milk thistle ( Silybum marianum ). Silymarin is an effective SARS-CoV-2 main protease (M pro ) inhibitor. Silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance. Silymarin has the chemopreventive effect on hepatocellular carcinoma (HCC). Silymarin has the potential for COVID-19 research.
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