NX-5948

NX-5948
  • CAS No.:2649400-34-8
  • Formula:C42H54N12O5
  • M.W.:807

Overview

NX-5948 is an orally active chimeric targeting molecule that selectively degrades BTK via the cereblon E3 ligase complex. It inhibits B cell activation, reduces tumor growth in xenograft models, and is effective in collagen-induced arthritis, all while crossing the blood-brain barrier. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

  • Catalog No.: BP-42254
  • CAS No.: 2649400-34-8
  • Molecular Formula: C42H54N12O5
  • Molecular Weight: 807
  • Storage: -20°C
  • Availability: 24 Hours

Source

Original product source


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