Ara-guanosine Triphosphate (Ara-GTP), the arabinofuranosyl guanine 5′-triphosphate of nelarabine, pairs a 2′-inverted arabinosyl sugar, guanine base, and high-energy γ-β-α phosphates, seamlessly replacing dGTP in DNA to halt polymerases and provoke lethal strand damage.
Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleotides | Products > Nucleoside, Nucleotide, Phosphoramidite > Nucleotides > Triphosphate
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