Golcadomide is a potent, orally active modulator of the CRBN E3 ligase. It engages with the CRL4-CRBN complex, promoting the recruitment and ubiquitin-dependent degradation of the transcription factors Ikaros and Aiolos. This selective modulation of protein degradation pathways highlights its utility for research in cell regulation and related fields. Reagent-grade; for laboratory research purposes only.
Products > PROTAC, Molecular glue > Ligands
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