1,2-Dierucoyl-sn-glycero-3-PE

Overview

1,2-Dierucoyl-sn-glycero-3-PE is a phospholipid containing erucic acid (13(Z)-docosenoic acid at the sn-1 and sn-2 positions. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. 1,2-Dierucoyl-sn-glycero-3-PE has also been used in the synthesis of various PEG-conjugates for incorporation into liposomes. LNPs containing 1,2-dierucoyl-sn-glycero-3-PE and encapsulating mRNA encoding human erythropoietin (hEPO) increase serum hEPO levels in mice.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Helper Lipid | PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Phospholipid | Drug Delivery, Surface Modification > Lipid Molecules > Helper Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Phospholipid | Products > Lipids In Drug Delivery > Helper Lipid | Products > Lipids In Drug Delivery > Helper Lipid > Phosphatidylethanolamine | Products > Lipids In Drug Delivery > Phospholipid > Phosphatidylethanolamine | Products > Lipids In Drug Delivery > Activated Lipid > Lipid Amine

Product Information

• Catalog No.: BP-45378
• CAS No.: 904304-57-0
• Molecular Formula: C49H94NO8P
• Molecular Weight: 856.3
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source