Stibophen is a potent antiparasitic agent is effective against Litomosoides carinii , Dipetalonema witei , and Brugia pahangi . Stibophen inhibits lactate accumulation and phosphofructokinases ( PFK ) activity in adult filariids. Stibophen also inhibits Ascaris and Hymenolepis diminuta PFK without inhibiting mammalian liver PFK. Stibophen can be used for the research of schistosomiasis and filariid infections.
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