7-Hydroxyquinoline

CAS No.：580-20-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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7-Hydroxyquinoline Basic information

Product Name:	7-Hydroxyquinoline
Synonyms:	7-HYDROXYQUINOLINE 99%;1H-Quinolin-7-one;7-Hydroxyquinoline,99%;7-Hydroxyquinoline, 99% 1GR;7-QUINOLINOL HYDRATE;7-Quinolinol (8CI,9CI);CCRIS 4332;7-HYDROXYQUINOLINE
CAS:	580-20-1
MF:	C9H7NO
MW:	145.16
EINECS:	209-457-2
Product Categories:	Hydroxyquinolines;Quinolines;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Heterocycles
Mol File:	580-20-1.mol

7-Hydroxyquinoline Chemical Properties

Melting point	239-244 °C
Boiling point	264.27°C (rough estimate)
density	1.1555 (rough estimate)
refractive index	1.4500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Powder
pka	pK1:5.48(＋1);pK2:8.85(0) (20°C)
color	Beige to pale brown
Water Solubility	454.3mg/L(20 ºC)
CAS DataBase Reference	580-20-1(CAS DataBase Reference)
NIST Chemistry Reference	7-Quinolinol(580-20-1)
EPA Substance Registry System	7-Quinolinol (580-20-1)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	36/37/38-20/21/22-22
Safety Statements	36/37/39-26
RTECS	VC4160000
HazardClass	IRRITANT
HS Code	29334900

MSDS Information

Provider	Language
7-Hydroxyquinoline	English
ACROS	English

7-Hydroxyquinoline Usage And Synthesis

Chemical Properties	white to light yellow crystal powder
Definition	ChEBI: A monohydroxyquinoline carrying a hydroxy substituent at position 7.

7-Hydroxyquinoline Preparation Products And Raw materials

Raw materials

Ethanol-->Hydrochloric acid-->Methanol-->Tetrahydrofuran-->Dichloromethane-->Potassium hydroxide-->Triethylamine-->Dimethyl sulfoxide-->Tosyl chloride-->Acrolein-->3-Aminophenol-->Benzenesulfonamide, N-(3-hydroxyphenyl)-4-methyl-N-(3-oxopropyl)--->7-Quinolinol, 1,2-dihydro-1-[(4-methylphenyl)sulfonyl]--->7-Bromoquinoline-->7-methoxyquinoline-->N-(m-hydroxyphenyl)-p-toluenesulphonamide-->7-Hydroxy-1,2,3,4-tetrahydroquinoline

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