Dimethyl acetylsuccinate

Dimethyl acetylsuccinate
  • CAS No.:10420-33-4
Other grades of this product :
Dimethyl acetylsuccinate Basic information
Product Name:Dimethyl acetylsuccinate
Synonyms:acetyl-butanedioicaciddimethylester;acetyl-butanedioicacidimethylester;ACETYLSUCCINIC ACID DIMETHYL ESTER;DMAS;DIMETHYL ACETYLSUCCINATE;BUTANEDIOIC ACID, ACETYL-DIMETHYL ESTER;BUTANDIOIC ACID ACETYL-DIMETHYLESTER;Doimethyl Acetylsuccinate
CAS:10420-33-4
MF:C8H12O5
MW:188.18
EINECS:233-897-4
Product Categories:Pharmaceutical Intermediates;C8 to C9;Carbonyl Compounds;Esters;bc0001
Mol File:10420-33-4.mol
Dimethyl acetylsuccinate Chemical Properties
Melting point 33 °C (lit.)
Boiling point 129-134 °C/12 mmHg (lit.)
density 1.16 g/mL at 25 °C (lit.)
vapor pressure 19.6Pa at 25℃
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility 30g/l OECD Test Guideline 105
pka10.53±0.59(Predicted)
form Notspecified
color White or Colorless to Almost white or Almost colorless
explosive limit0.72-11.1%(V)
LogP0.69 at 35℃ and pH7
CAS DataBase Reference10420-33-4(CAS DataBase Reference)
EPA Substance Registry SystemButanedioic acid, acetyl-, dimethyl ester (10420-33-4)
Safety Information
WGK Germany 1
TSCA Yes
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Dimethyl acetylsuccinate Usage And Synthesis
UsesDimethyl Acetylsuccinate was used in preparation of β-carbolines via diastereo- and enantioselective Bronsted acid catalyzed N-acyliminium cyclization cascades of tryptamines and keto acids/esters.
UsesDimethyl acetylsuccinate has been used in the synthesis of 2-oxofuro[2,3-b]pyrroles and 19-methyl-15-oxa-20-azatricyclo[12.3.3.0(1,14)]icos-18-en-18-carboxylates.
General DescriptionDimethyl acetylsuccinate undergoes sulfuric acid catalyzed Pechmann condensation with the corresponding resorcinol derivative to give 7-hydroxycoumarins.
Dimethyl acetylsuccinate Preparation Products And Raw materials

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