N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI&

CAS No.：10563-29-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Basic information

Product Name:	N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI&
Synonyms:	N-(3-Dimethylaminopropyl)-1,3-propanediamine;N-[3-(Dimethylamino)propyl]-1,3-propanediamine;1,3-Propanediamine, N3-(3-aminopropyl)-N1,N1-dimethyl-;Brn 2715375;Einecs 234-148-4;N,N-Dimethyldipropylenetriamine,DMAPAPA;N N'-DIMETHYLDIPROPY;N′-(3-Aminopropyl)-N,N-dimethyl-1,3-propandiamin
CAS:	10563-29-8
MF:	C8H21N3
MW:	159.27
EINECS:	234-148-4
Product Categories:	Nitrogen Compounds;Organic Building Blocks;Polyamines
Mol File:	10563-29-8.mol

N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Chemical Properties

Boiling point	220 °C(lit.)
density	0.883 g/mL at 25 °C(lit.)
vapor pressure	3Pa at 20℃
refractive index	n20/D 1.4630(lit.)
Fp	220 °F
pka	10.32±0.19(Predicted)
Water Solubility	1000g/L at 25℃
LogP	-0.56 at 25℃
EPA Substance Registry System	1,3-Propanediamine, N'-(3-aminopropyl)-N,N-dimethyl- (10563-29-8)

Safety Information

Hazard Codes	C
Risk Statements	21/22-34
Safety Statements	23-26-36/37/39-45
RIDADR	UN 2735 8/PG 2
WGK Germany	1
RTECS	TX7000000
HazardClass	8
PackingGroup	III
Toxicity	LD50 orl-unr: 1432 mg/kg GTPZAB 28(11),50,84

MSDS Information

N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Usage And Synthesis

Uses	N,N-Dimethyldipropylenetriamine (DP) may be used to: Prepare poly(ethylene oxide)-b-poly(3-caprolactone-g-DP) [PEO-b-P(CL-g-DP)], a biodegradable amphiphilic polycationic copolymer. Develop a second generation aminoglycoside 6′-N-acetyltransferase (AAC(6′) inhibitor. Prepare a hydrophilic gemcitabine conjugated cationic copolymer, which can be employed in the treatment pancreatic cancer.
General Description	N,N-Dimethyldipropylenetriamine is an aliphatic acyclic amine that is commonly used to develop polymeric system for gene delivery.
Flammability and Explosibility	Nonflammable
Safety Profile	A poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.

N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Preparation Products And Raw materials

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