Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate

CAS No.：328086-60-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate Basic information

Product Name:	Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate
Synonyms:	(αS,3S)-α-[(tert-Butyloxycarbonyl)aMino]-2-oxo-3-pyrrolidinepropanoic acid Methyl Ester;methyl (S)-2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate;(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate(WXG01709);(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate;Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate;3-Pyrrolidinepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-, methyl ester, (αS,3S)-;Methyl (αS,3S)-α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-3-pyrrolidinepropanoate;(S)-METHYL 2-((TERT-BUTOXYCARBONYL)AMINO)-
CAS:	328086-60-8
MF:	C13H22N2O5
MW:	286.33
EINECS:
Product Categories:	Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals;1
Mol File:	328086-60-8.mol

Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate Chemical Properties

Melting point	110-114°C
Boiling point	471.5±20.0 °C(Predicted)
density	1.142±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer, Under inert atmosphere
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	10.97±0.46(Predicted)
form	Solid
color	White to Off-White

Safety Information

HS Code

2933399990

MSDS Information

Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate Usage And Synthesis

Description	Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate is a carboxylate derivative and can be used as a pharmaceutical intermediate.Used in the preparation of protease inhibitor.
Uses	(αS,3S)-α-[(tert-Butyloxycarbonyl)aMino]-2-oxo-3-pyrrolidinepropanoic acid Methyl Ester is used in the preparation of protease inhibitor.

Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate Preparation Products And Raw materials

Raw materials

L-Glutamic acid, 4-(2-aminoethyl)-N-[(1,1-dimethylethoxy)carbonyl]-, 1,5-dimethyl ester, (4S)--->(4R)-N-(tert-Butyloxycarbonyl)-4-(cyanoMethyl)-L-glutaMic Acid 1,5-DiMethyl Ester-->Di-tert-butyl dicarbonate-->L-Glutamic acid

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