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| 1,8-Naphthyridine Basic information |
| Product Name: | 1,8-Naphthyridine | | Synonyms: | 1,8-DIAZANAPHTHALENE;1,8-NAPHTHYRIDINE;PYRIDO[2,3-B]PYRIDINE;1,8-Pyridopyridine;1,8-Naphthyridine(6CI,7CI,8CI,9CI);1,8-NAPHTHYRIDINE 98+%;1,8-Diazanapthalene;1,8-Diazanaphthalene
Pyrido[2,3-b]pyridine | | CAS: | 254-60-4 | | MF: | C8H6N2 | | MW: | 130.15 | | EINECS: | | Product Categories: | PYRIDINE | | Mol File: | 254-60-4.mol |
| 1,8-Naphthyridine Chemical Properties |
| Melting point | 99.8-99.9°C | | Boiling point | 248.9±13.0 °C(Predicted) | | density | 1.183±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 3.39 | | form | powder to crystal | | pka | 3.55±0.10(Predicted) | | color | White to Light yellow to Light orange | | InChIKey | FLBAYUMRQUHISI-UHFFFAOYSA-N | | CAS DataBase Reference | 254-60-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | HazardClass | IRRITANT | | HS Code | 2902900000 |
| 1,8-Naphthyridine Usage And Synthesis |
| Description | 1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones. | | Uses | 1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands. | | Definition | ChEBI: 1,8-naphthyridine is a naphthyridine in which the nitrogens are situated at positions 1 and 8. | | Purification Methods | Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.] |
| 1,8-Naphthyridine Preparation Products And Raw materials |
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