Other grades of this product :
| Ziconotide acetate Basic information |
| Product Name: | Ziconotide acetate | | Synonyms: | OMEGA-CONOTOXIN MVIIA;OMEGA-CGTX MVII A;ZICONOTIDE ACETATE;snx111;H-CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2;H-CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2 (DISULFIDE BRIDGE: 1-16, 8-20, AND 15-25);CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2;CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 (DISULFIDE BRIDGE: 1-16,8-20, AND 15-25) | | CAS: | 107452-89-1 | | MF: | C102H172N36O32S7 | | MW: | 2639.13 | | EINECS: | | Product Categories: | Peptide | | Mol File: | 107452-89-1.mol |
| Ziconotide acetate Chemical Properties |
| density | 1.60±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | InChIKey | BPKIMPVREBSLAJ-QTBYCLKRSA-N |
| Ziconotide acetate Usage And Synthesis |
| Uses | Ligand for binding studies of voltage sensitive calcium channels. | | Uses | Ziconotide, the peptide toxin of the Conus magus (cone snail) is a selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective. | | Brand name | Prialt (Elan). | | General Description | ω-Conotoxin MVIIA functions as a selective inhibitor of N-type voltage-sensitive calcium channels (VSCCs). It has analgesic and neuroprotective effects. ω-Conotoxin MVIIA is used to treat neuropathic pain. | | Biochem/physiol Actions | Neuronal N-type Ca2+ channel blocker in mammalian and amphibian brain; blocks release of GABA and glutamate at neuronal synapses. |
| Ziconotide acetate Preparation Products And Raw materials |
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