2-Vinylpyridine

2-Vinylpyridine
  • CAS No.:100-69-6
Other grades of this product :
2-Vinylpyridine Basic information
Product Name:2-Vinylpyridine
Synonyms:2-Vinylpyridine, Stab. With 0.1% 4-Tert-Butylcatechol;2-Vinylpyridine, stabilized, 97% 5ML;2-ethenyl-pyridin;2-Pyridylethylene;2-vinyl-pyridin;Betahistine Impurity 1(Betahistine EP Impurity A);2-VINYLPYRIDINE;2VP
CAS:100-69-6
MF:C7H7N
MW:105.14
EINECS:202-879-8
Product Categories:Aromatics, Heterocycles, Impurities, Intermediates;Monomers;Polymer Science;Vinyl Halides, Amines, Amides, and Other Vinyl Monomers;C7 and C8;Heterocyclic Building Blocks;Pyridines derivates;Pyridines
Mol File:100-69-6.mol
2-Vinylpyridine Chemical Properties
Melting point -50 °C
Boiling point 79-82 °C29 mm Hg(lit.)
density 0.975 g/mL at 25 °C(lit.)
vapor pressure 10 mm Hg ( 44.5 °C)
refractive index n20/D 1.549(lit.)
Fp 116 °F
storage temp. Store at -20°C.
solubility 27g/l
form Liquid
pkapK1:4.98(+1) (25°C)
color Clear brown
PH8 (100g/l, H2O, 20℃)
explosive limit1.3-10.7%(V)
Water Solubility 2.5 g/100 mL (20 ºC)
BRN 104505
Stability:Unstable; may be stabilized with a small amount of ter-butyl catechol. Heat sensitive - store cold. Flammable. Incompatible with strong oxidizing agents, strong bases, strong acids.
InChIKeyKGIGUEBEKRSTEW-UHFFFAOYSA-N
LogP1.54 at 25℃
CAS DataBase Reference100-69-6(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 2-ethenyl-(100-69-6)
EPA Substance Registry System2-Vinylpyridine (100-69-6)
Safety Information
Hazard Codes T,C,F,N
Risk Statements 10-20-25-34-42/43-36-51/53-43-21/22
Safety Statements 16-23-26-36/37/39-45-28A-61
RIDADR UN 3073 6.1/PG 2
WGK Germany 3
RTECS UU1040000
8-19
Autoignition Temperature440 °C
Hazard Note Toxic
TSCA Yes
HazardClass 6.1
PackingGroup II
HS Code 29333999
Hazardous Substances Data100-69-6(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 100 mg/kg
MSDS Information
ProviderLanguage
2-Vinylpyridine English
SigmaAldrich English
ACROS English
ALFA English
2-Vinylpyridine Usage And Synthesis
Chemical PropertiesThe odor of 2-vinylpyridine can be detected at exposure levels below 1 ppm (v/v). The unpleasant odor can be tolerated at concentrations that can produce acute symptoms and irritation. Special precautions should be taken to avoid skin and eye contact, as well as inhalation of the vapor.
Chemical Propertiesdark brown liquid with an unpleasant odour
Uses2-Vinylpyridine is a pyridine deriviative used in the preparation of poly(2-vinylpyridine) via radical polymerization. 2-Vinylpyridine is used to improve effectiveness of protective polymer coatings o n metals. 2-Vinylpyridine is an impurity of Betahistine (B324000).
Uses2-Vinylpyridine is a pyridine derivative used in the preparation of poly(2-vinylpyridine) via radical polymerization. 2-Vinylpyridine is used to improve effectiveness of protective polymer coatings on metals. It is a reagent for pyridylethylation for new protection method for active hydrogen compounds.. It is also used as basic materials for one of largest-selling plastic, manufacturing pharmaceuticals and bio-compounds.
General Description2-Vinylpyridine (2VP) is a water soluble pyridine derivative that can be used in the synthesis of poly(2-vinylpyridine) (P2VP) by anionic polymerization. It can be industrially prepared by treatment of 2-methylpyridine with an aqueous solution of formaldehyde in a temperature range of 150-200°C.
Flammability and ExplosibilityFlammable
CarcinogenicityNo definitive information on carcinogenicity of the vinylpyridines was found. However, when either 2-vinylpyridine or 4-vinylpyridine was injected intraperitoneally into A/J mice (200 mmol/animal), there was no significant increase in lung adenoma or any other tumors. None was listed as a carcinogen by IARC, OSHA, NTP, and ACGIH.
Purification MethodsSteam distil it, then dry it with MgSO4 and distil it in a vacuum. [Beilstein 20 H 256, 20 III/IV 2884, 20/6 V 211.]

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