Other grades of this product :
| 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Basic information |
| Product Name: | 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester | | Synonyms: | GSK-0660, >=98%;3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester;GSK 0660;Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate;2-Thiophenecarboxylic acid, 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-, methyl ester;4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine;METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE;3-(2-Methoxy-4-phenylamino-phenylsulfamoyl)-thiophene-2-carboxylic acid methyl ester | | CAS: | 1014691-61-2 | | MF: | C19H18N2O5S2 | | MW: | 418.49 | | EINECS: | | Product Categories: | Inhibitors | | Mol File: | 1014691-61-2.mol |
| 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Chemical Properties |
| Boiling point | 608.1±65.0 °C(Predicted) | | density | 1.413±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear | | form | powder | | pka | 8.51±0.50(Predicted) | | color | white to beige | | InChIKey | NDFKBGWLUHKMFY-UHFFFAOYSA-N |
| 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Usage And Synthesis |
| Uses | GSK0660 has been used to study the effects of bezafibrate (BZA) on hypertrophy. | | General Description | GSK0660 has antiangiogenic property in oxygen-induced retinopathy. It also regulates tumor necrosis factor-α (TNFα)-induced inflammation in human retinal microvascular endothelial cells (HRMECs). | | Biochem/physiol Actions | GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (160 nM). GSK0660 is nearly inactive on PPARα and PPARγ with IC50s greater than 10 μM. |
| 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Preparation Products And Raw materials |
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![3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester](/img/1014691-61-2.jpg "3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester")
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