-N7-DGTP

-N7-DGTP
  • CAS No.:101515-08-6
Other grades of this product :
-N7-DGTP Basic information
Product Name:-N7-DGTP
Synonyms:7-DEAZA-2'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE LITHIUM SALT;7-DEAZA-2'-DEOXYGUANOSINE-5'-TRIPHOSPHORIC ACID, LITHIUM;7-DEAZA-DGTP, LI;7-DEAZA-DGTP LITHIUM SALT;-N7-DGTP;7-deaza-2'-deoxyguanosine 5'-*triphosphate lithiu;7-DEAZA-2'-DEOXYGUANOSINE 5'-*TRIPHOSPHA TE LITHIUM;2'-deoxy-7-deazaguanosine triphosphate
CAS:101515-08-6
MF:C11H17N4O13P3
MW:506.19
EINECS:
Product Categories:Pharmaceutical
Mol File:101515-08-6.mol
-N7-DGTP Chemical Properties
density 2.48±0.1 g/cm3(Predicted)
storage temp. -20°C
pka0.97±0.50(Predicted)
form solution
color colorless
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
-N7-DGTP Usage And Synthesis
Uses7-Deaza-dGTP is a substrate for most DNA polymerases, including Taq DNA polymerase.7-Deaza-dGTP is used in the dideoxy-chain termination sequencing methods, in place of dGTP to overcome compression problems in gel electrophoresis when sequencing GC-rich stretches of DNA.Partial substitution of 7-Deaza-dGTP for dGTP in PCRs can improve the product yield when the template is GC-rich (i.e., has extensive secondary structures).
General Description7-Deaza-2′-deoxyguanosine 5′-triphosphate enhances polymerase chain reaction (PCR) product yield.
Biochem/physiol ActionsThis dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases.
-N7-DGTP Preparation Products And Raw materials

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