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| ACETOACETYL COENZYME A SODIUM SALT Basic information |
| Product Name: | ACETOACETYL COENZYME A SODIUM SALT | | Synonyms: | Coenzyme A,S-(3-oxobutanoate), tetrasodium salt (9CI);[5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[[3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[2-(3-oxobutanoylsulfanyl)ethylamino]propyl]amino]butoxy]-oxidophosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-yl] phosphate;ACETOACETYL COENZYME A TRISODIUM SALT &;ACETOACETYL COENZYME A SODIUM;Acetoacetyl coenzyme A;coenzyme A acetoacetyl derivative trisodium salt hydrate;Acetoacetyl coenzyme A hydrate sodium salt;Acetoacetyl coenzyme A sodium salt hydrate,Acetoacetyl-CoANa3 | | CAS: | 102029-52-7 | | MF: | C25H37N7Na3O18P3S | | MW: | 917.55 | | EINECS: | | Product Categories: | | Mol File: | 102029-52-7.mol |
| ACETOACETYL COENZYME A SODIUM SALT Chemical Properties |
| storage temp. | −20°C | | solubility | H2O: 50 mg/mL, clear, colorless to faintly yellow |
| ACETOACETYL COENZYME A SODIUM SALT Usage And Synthesis |
| Purification Methods | Purification can be carried out by passage through a DEAE-cellulose formate column, then through a Dowex 50 (H+) column to remove Na ions, concentrated by lyophilisation and redissolved in H2O. It is commercially available as a solution of 0.05g/mL of H2O. The concentration of acetoacetylcoenzyme A is determined by the method of Stern et al. [J Biol Chem 221 15 1956]. It is stable at pH 7-7.5 for several hours at 0o (half-life ca 1-2hours). At room temperature it is hydrolysed in ca 1-2hours at pH 7-7.5. At pH 1.0/20o it is more stable than at neutrality. A solution of the trisodium salt (0.05g/mL H2O) adjusted to pH 5 with 2N NaOH can be stored frozen for several weeks. It is stable at pH 2-3/-17o for at least 6 months. [Hersch & Jencks J Biol Chem 242 3468 1967, Clikenbeard et al. J Biol Chem 250 3108 1975, Simon & Shemin J Am Chem Soc 75 2520 1953, Moffatt & Khorana 81 1265 1959, Salem et al. Biochem J 258 563 1989, Beilstein 26 III/IV 3668.] |
| ACETOACETYL COENZYME A SODIUM SALT Preparation Products And Raw materials |
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