JTV-519

CAS No.：1026399-42-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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JTV-519 Basic information

Product Name:	JTV-519
Synonyms:	1-(2,3-Dihydro-7-Methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylMethyl)cyclohexyl]-1-propanone;JTV-519;K201;3-(4-benzylcyclohexyl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one;1-Propanone, 1-(2,3-dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)cyclohexyl]-
CAS:	1026399-42-7
MF:	C26H33NO2S
MW:	423.61
EINECS:
Product Categories:	Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:	1026399-42-7.mol

JTV-519 Chemical Properties

Boiling point	606.9±55.0 °C(Predicted)
density	1.123±0.06 g/cm3(Predicted)
pka	-0.79±0.20(Predicted)

Safety Information

MSDS Information

JTV-519 Usage And Synthesis

Uses	K201 is a benzothiazepine derivative that has been shown to possess anti-arrhythmic and cardioprotective properties. Recent studies suggest that suppression of spontaneous Ca2+ release and the activity of RyR2 contributes, at least in part, to the anti-arrhythmic properties of K201.

JTV-519 Preparation Products And Raw materials

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