XPhos Pd G1

XPhos Pd G1
  • CAS No.:1028206-56-5
Other grades of this product :
XPhos Pd G1 Basic information
Reaction
Product Name:XPhos Pd G1
Synonyms:XPhos Palladacycle;XPhos precatalyst;[2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1);Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) ;XPhos Pd G1;Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct;XPhos Pd;Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1]
CAS:1028206-56-5
MF:C41H59ClNPPd
MW:738.77
EINECS:633-034-5
Product Categories:Buchwald Ligands&Precatalysts;Buchwald Precatalysts Series;Pd
Mol File:1028206-56-5.mol
XPhos Pd G1 Chemical Properties
Melting point 205-210°C
form Powder
color white
CAS DataBase Reference1028206-56-5
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-52/53
Safety Statements 26-61
WGK Germany 3
HS Code 2843909000
MSDS Information
XPhos Pd G1 Usage And Synthesis
Reaction
  1. Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides.
  2. Catalyst for rapid C-N bond-forming process at low catalyst loading.
  3. Catalyst for C-N cross-coupling reactions, at or below room temperature.
  4. Catalyst for the synthesis of tetracyclic indoles via intermolecular α-arylation of ketones.
  5. Catalyst for the cross-coupling of benzyl chlorides with cyclopropanol-derived ketone homoenolates
UsesXPhos Pd G1 is used as androgen receptor modulator for treatment of disorders including prostate cancer.
UsesApplication Guide for Palladium Catalyzed Cross-Coupling ReactionsCatalyst used for:
  • Amination / cyclization reactions
  • C-N bond-forming reactions via packed-bed microreactors
  • Boration of aryl chlorides
  • Arylation of oxazole
  • Cross-coupling reactions
General DescriptionMaterial may contain up to 5% pentane
XPhos Pd G1 Preparation Products And Raw materials

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