CTAP

CTAP
  • CAS No.:103429-32-9
Other grades of this product :
CTAP Basic information
Product Name:CTAP
Synonyms:H-D-PHE-CYS-TYR-D-TRP-ARG-THR-PEN-THR-NH2;D-PHE-CYS-TYR-D-TRP-ARG-THR-PEN-THR-NH2;CTAP;CYS2, TYR3, ARG5, PEN7-AMIDE;H-D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2(Cys2-Pen7);CTAP, ≥95%;7)-disulfide;M.W. 1104.30 C51H69N13O11S2
CAS:103429-32-9
MF:C51H69N13O11S2
MW:1104.3
EINECS:
Product Categories:Neuropeptides;Opioid Peptides;Peptide;Other Opioid Peptides;Other Opioid PeptidesPeptides for Cell Biology;Opioid receptor and opioid-like receptor
Mol File:103429-32-9.mol
CTAP Chemical Properties
storage temp. -20°C
form Solid
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
CTAP Usage And Synthesis
UsesCTAP acts as a selective μ-opioid receptor antagonist with a multitude of applications including the regulation of aggressive behavior in mammals. Activation of μ-opioid receptors in the central nucleus of the amygdala, is responsible for mechanisms related to the control of sodium appetite and regulation of sodium intake.
UsesCTAP has been used as a μ-opioid receptor (MOR) antagonist:
  • to study the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitor isoleucine-proline-isoleucine (IPI) and vildagliptin in carrageenan-induced inflammation
  • to study the role of MOR in glutamate and gamma-aminobutyric acid (GABA) efflux during predator stress in rats
  • to determine the endogenous opioid peptide involved in blocking pain induced by activated gastrin-releasing peptide (Grp+) neurons
Biochem/physiol ActionsCTAP is a peptide antagonist produced from somatostatin analogs.
CTAP Preparation Products And Raw materials

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