BOC-11-AMINOUNDECANOIC ACID

CAS No.：10436-25-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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BOC-11-AMINOUNDECANOIC ACID Basic information

Product Name:	BOC-11-AMINOUNDECANOIC ACID
Synonyms:	BOC-11-AMINOUNDECANOIC ACID;BOC-11-AMINOUNDECYLIC ACID;BOC-11-AUN-OH;BOC-NH-(CH2)10-COOH;11-(BOC-AMINO)-UNDECANOIC ACID;T-BUTOXYCARBONYL-11-AMINOUNDECANOIC ACID;T-BUTOXYCARBONYL-11-AMINOUNDECYLIC ACID;N-TERT-BUTYLOXYCARBONYL-11-AMINO-UNDECANOIC ACID
CAS:	10436-25-6
MF:	C16H31NO4
MW:	301.42
EINECS:
Product Categories:	Amino Acids
Mol File:	10436-25-6.mol

BOC-11-AMINOUNDECANOIC ACID Chemical Properties

Melting point	67-68 °C
Boiling point	441.9±18.0 °C(Predicted)
density	1.006±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	4.78±0.10(Predicted)
form	powder to crystal
color	White to Almost white
BRN	1975656
CAS DataBase Reference	10436-25-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25
WGK Germany	3
HazardClass	IRRITANT

MSDS Information

Provider	Language
SigmaAldrich	English

BOC-11-AMINOUNDECANOIC ACID Usage And Synthesis

Description

Boc-11-aminoundecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

White powder

BOC-11-AMINOUNDECANOIC ACID Preparation Products And Raw materials

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