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| METHYLMALONYL COENZYME A LITHIUM Basic information |
| Product Name: | METHYLMALONYL COENZYME A LITHIUM | | Synonyms: | METHYLMALONYL COENZYME A LITHIUM;METHYLMALONYL COENZYME A TETRALITHIUM &;methylmalonyl coenzyme a tetralithium salt hydrate;α-methylmalonyl coenzyme a tetralithium salt;3-[2-[3-[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]aminopropanoylamino]ethylsulfanyl]-2-methyl-3-oxo-propanoic acid;Methylmalonyl-CoA;coenzyme A methylmalonyl derivative, tetralithium hydrate;coenzyme A methylmalonyl derivative, lithium salt | | CAS: | 104809-02-1 | | MF: | C25H41LiN7O19P3S | | MW: | 875.55 | | EINECS: | | Product Categories: | | Mol File: | 104809-02-1.mol |
| METHYLMALONYL COENZYME A LITHIUM Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: 50 mg/mL, clear, colorless |
| METHYLMALONYL COENZYME A LITHIUM Usage And Synthesis |
| Uses | Methylmalonyl coenzyme A (CoA) has been used in the preparation of the calibration curve in ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS). It has also been used in the measurement of methylmalonyl-CoA mutase and methylmalonyl-CoA epimerase activity. | | Biochem/physiol Actions | Methylmalonyl coenzyme A (CoA) is a catabolite of odd-chain fatty acids, cholesterol and few amino acids like valine, isoleucine, methionine, threonine. It is produced by the activity of the enzyme propionyl-CoA carboxylase(PCC). Methylmalonyl coenzyme A (CoA) is converted to succinyl-CoA by the methylmalonyl-CoA mutase (MCM) and vitamin B12 as the cofactor. Either a low MCM activity or an altered metabolism of vitamin B12 causes the inherited metabolic disease methylmalonic acidemia (MMA). |
| METHYLMALONYL COENZYME A LITHIUM Preparation Products And Raw materials |
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