Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride

Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride
  • CAS No.:1049741-81-2
Other grades of this product :
Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Basic information
Product Name:Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride
Synonyms:Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride
CAS:1049741-81-2
MF:C16H19ClN2O2
MW:306.78726
EINECS:
Product Categories:
Mol File:1049741-81-2.mol
Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Chemical Properties
storage temp. 2-8°C
solubility DMSO: soluble30mg/mL
form solid
color off-white
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
MSDS Information
Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Usage And Synthesis
UsesCiproxifan Hydrochloride is a novel chemical series of human histamine H3-receptor antagonists.
Biochem/physiol ActionsCiproxifan belongs to a novel chemical series of histamine H3-receptor antagonists. In vitro, it behaved as a competitive antagonist at the H3 autoreceptor controlling 3H histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with 125I-iodoproxyfan. Ciproxifan appears to be an orally bioavailable, extremely potent and selective H3-receptor antagonist whose vigilance- and attention-promoting effects are promising for therapeutic applications in aging disorders.
Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Preparation Products And Raw materials

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