Other grades of this product :
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Basic information |
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble30mg/mL | | form | solid | | color | off-white |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Usage And Synthesis |
| Uses | Ciproxifan Hydrochloride is a novel chemical series of human histamine H3-receptor antagonists. | | Biochem/physiol Actions | Ciproxifan belongs to a novel chemical series of histamine H3-receptor antagonists. In vitro, it behaved as a competitive antagonist at the H3 autoreceptor controlling 3H histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with 125I-iodoproxyfan. Ciproxifan appears to be an orally bioavailable, extremely potent and selective H3-receptor antagonist whose vigilance- and attention-promoting effects are promising for therapeutic applications in aging disorders. |
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Preparation Products And Raw materials |
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