TGF-ALPHA

TGF-ALPHA
  • CAS No.:105186-99-0

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
TGF-ALPHA Basic information
Product Name:TGF-ALPHA
Synonyms:HUMAN TGF-ALPHA;HUMAN TGF-A;HUMAN TRANSFORMING GROWTH FACTOR ALPHA;H-VAL-VAL-SER-HIS-PHE-ASN-LYS-CYS-PRO-ASP-SER-HIS-THR-GLN-TYR-CYS-PHE-HIS-GLY-THR-CYS-ARG-PHE-LEU-VAL-GLN-GLU-GLU-LYS-PRO-ALA-CYS-VAL-CYS-HIS-SER-GLY-TYR-VAL-GLY-VAL-ARG-CYS-GLU-HIS-ALA-ASP-LEU-LEU-ALA-OH;ETGF;SARCOMA GROWTH FACTOR;RAT TGF-ALPHA;RECOMBINANT HUMAN TGF-A
CAS:105186-99-0
MF:C239H348N70O72S6
MW:5546.13622
EINECS:
Product Categories:
Mol File:105186-99-0.mol
TGF-ALPHA Chemical Properties
storage temp. -20°C
form powder
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
TGF-ALPHA Usage And Synthesis
UsesTransforming Growth Factor-α human has been used:
  • to determine the ideal concentration of growth factors to be used in the culture medium that supports sheep preantral follicles
  • in human hepatocytes cell culture and keratinocyte cell culture
  • to induce morphogenesis in primary mouse organoids
General DescriptionThe TNFα (tumor necrosis factor α) gene is mapped to human chromosome 6p21.33. TNFα is a member of TNF superfamily.
Biochem/physiol ActionsThe TNFA gene is significantly associated with the regulation of innate and adaptive immune responses. Polymorphism of TNFA gene is known to cause acute motor axonal neuropathy. The cytokine release and gene action is associated with epithelial cells, myeloid cells, endothelial, as well as tumor cells. Tumor cells are known to release TNFA, specifically in response to chemotherapy.
TGF-ALPHA Preparation Products And Raw materials

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