NOR-BINALTORPHIMINE DIHYDROCHLORIDE

CAS No.：105618-26-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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NOR-BINALTORPHIMINE DIHYDROCHLORIDE Basic information

Product Name:	NOR-BINALTORPHIMINE DIHYDROCHLORIDE
Synonyms:	N-DESMETHYLBINALTORPHIMINE;NOR-BINALTORPHIMINE DIHYDROCHLORIDE;NORBNI;NOR-BNI DIHYDROCHLORIDE;NOR-BNL 2HCL;norbinaltorphimine;4,8:11,15-DIMETHANO-20H-BISBENZOFURO[2,3-A:3',2'-I]DIPYRIDO[4,3-B:3',4'-H]CARBAZOLE-1,8A,10A,18-TETROL, 7,12-BIS(CYCLOPROPYLMETHYL)-5,6,7,8,9,10,11,12,13,14,19A,20B-DODECAHYDRO-, (4BS,8R,8AS,10AS,11R,14AS,19AR,20BR), DIHYDROCHLORIDE;17,17'-(DICYCLOPROPYLMETHYL)-6,6',7,7'-6,6'-IMINO-7,7'-BINORPHINAN-3,4',14,14'-TETROL DIHYDROCHLORIDE
CAS:	105618-26-6
MF:	C40H43N3O6
MW:	661.79
EINECS:
Product Categories:	Opioid receptor and opioid-like receptor;Opioids
Mol File:	105618-26-6.mol

NOR-BINALTORPHIMINE DIHYDROCHLORIDE Chemical Properties

density	1.63±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	artificial CSF: soluble2mg/mL (prepare with sonication for 4 minutes)
pka	9.11±0.60(Predicted)
color	tan
EPA Substance Registry System	Norbinaltorphimine (105618-26-6)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	-
RTECS	IO1320000

MSDS Information

Provider	Language
SigmaAldrich	English

NOR-BINALTORPHIMINE DIHYDROCHLORIDE Usage And Synthesis

Chemical Properties	Tan solid
Biological Activity	A selective κ -opioid receptor antagonist.
Biochem/physiol Actions	Highly selective k-opioid receptor antagonist. nor-Binaltorphimine has antidepressant properties.

NOR-BINALTORPHIMINE DIHYDROCHLORIDE Preparation Products And Raw materials

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