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| REC BETA-ECGF (HUMAN) Basic information |
| Product Name: | REC BETA-ECGF (HUMAN) | | Synonyms: | BETA-ENDOTHELIAL CELL GROWTH FACTOR, HUMAN, RECOMBINANT;BETA-ECGF;REC BETA-ECGF (HUMAN);REC BETA-ENDOTHELIAL CELL GROWTH FACTOR (HUMAN);RH-BETA-ECGF;B-endothelial cell growth factor*human recombinan;b-Endothelial Cell Growth Factor, Human, Recomb.;B-ENDOTHELIAL CELL GROWTH FACTOR*HUMAN R ECOMBINANT | | CAS: | 105843-51-4 | | MF: | | MW: | 0 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| REC BETA-ECGF (HUMAN) Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| REC BETA-ECGF (HUMAN) Usage And Synthesis |
| Uses | β-Endothelial Cell Growth Factor human has been used:- in cell death assay
- in endothelial cell culture
- in human umbilical vascular endothelial cell (HUVEC) culture
| | General Description | The β-endothelial cell growth factor (b-ECGF) gene encodes an angiogenic factor, and is mapped to human chromosome 11q13.1. Recombinant, human b-endothelial cell growth factor (b-ECGF) is a 14 amino acid N-terminal extension of acidic fibroblast growth factor. It is expressed in Escherichia coli. The 154 amino acid recombinant protein, generated after removal of the initiation methionine, has a predicted molecular mass of about 17 kDa. | | Biochem/physiol Actions | β-Endothelial cell growth factor (β-ECGF) is a potent endothelial cell mitogen and its mitogenic activity is potentiated by heparin. β-ECGF stimulates the growth of quiescent HUVEC cells in culture. β-ECGF is associated with lipid and glucose metabolism. This growth factor induces neovascularization in disease conditions. Upregulation of β-ECGF is observed in diabetic retinopathy, and polycystic ovary syndrome. It is also associated with tumor proliferation and invasion. β-ECGF increases fatty acid transport proteins expression to improve endothelial mediated lipid transpor. |
| REC BETA-ECGF (HUMAN) Preparation Products And Raw materials |
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