Other grades of this product :
| HUMAN ONCOSTATIN M Basic information |
| Product Name: | HUMAN ONCOSTATIN M | | Synonyms: | ONCOSTATIN M HUMAN RECOMBINANT CELL*CULT URE TESTED;ONCOSTATIN M, MOUSE RECOMBINANT,*EXPRESS ED IN E. CO;oncostatin m from mouse;ONCOSTATIN M (OSM), HUMAN, RECOMBINANT;Oncostatin M (209 aa) human;Oncostatin-M from rat;ONCOSTATIN M, HUMAN;ONCOSTATIN M, HUMAN, RECOMBINANT | | CAS: | 106956-32-5 | | MF: | C62H86N12O16 | | MW: | 0 | | EINECS: | 200-835-2 | | Product Categories: | | Mol File: | Mol File |
| HUMAN ONCOSTATIN M Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | color | white to off-white |
| HUMAN ONCOSTATIN M Usage And Synthesis |
| Uses | Human oncostatin-M has been used to stimulate bovine full-depth cartilage explants. It has also been used to culture embryonic stem cells in standard minimum essential medium-α. | | General Description | Oncostatin M (OSM) is produced by activated T cells, monocytes and Kaposi′s sarcoma cells. OSM shares several structural and functional characteristics with leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and ciliary neurotrophic factor (CNTF). | | Biochem/physiol Actions | Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. It can exert both stimulatory and inhibitory effects on cell proliferation. OSM stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi′s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release [e.g. interleukin-6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte-colony-stimulating factor (G-CSF)] from endothelial cells. |
| HUMAN ONCOSTATIN M Preparation Products And Raw materials |
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