| NPPB Basic information |
| Product Name: | NPPB |
| Synonyms: | 5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID;NPPB;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC A CID POTENT CHLORIDE CHANN;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%;3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid;Compound 144;C13705 |
| CAS: | 107254-86-4 |
| MF: | C16H16N2O4 |
| MW: | 300.31 |
| EINECS: | |
| Product Categories: | Chloride channel |
| Mol File: | 107254-86-4.mol |
| NPPB Chemical Properties |
| Melting point | 178-180℃ |
| Boiling point | 523.5±50.0 °C(Predicted) |
| density | 1.323±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | ethanol: 3 mg/mL |
| form | Yellow solid |
| pka | 2.27±0.22(Predicted) |
| Safety Information |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| NPPB Usage And Synthesis |
| Uses | Biochemical probe primarily as a Cl- channel blocker. |
| Uses | NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes. |
| Biological Activity | Very potent chloride channel blocker. |
| Biochem/physiol Actions | Potent chloride channel blocker. |
| NPPB Preparation Products And Raw materials |
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