COMU

COMU
  • CAS No.:1075198-30-9
Other grades of this product :
COMU Basic information
Product Name:COMU
Synonyms:(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate;4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate;1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate;4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium(COMU?);{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxy}dimethylamino(morpholin-4-yl)carbenium hexafluorophosp;(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.);COMU(R) 97%;elagolix intermediate 13
CAS:1075198-30-9
MF:C12H19F6N4O4P
MW:428.2678402
EINECS:682-899-5
Product Categories:
Mol File:1075198-30-9.mol
COMU Chemical Properties
Melting point ca 160℃
storage temp. Store at -15°C to -25°C.
solubility Soluble in DMF 1mmol in 2mL.
form Powder or Solid
color White to pale yellow
Sensitive Air & Moisture Sensitive
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HS Code 2934 99 90
MSDS Information
COMU Usage And Synthesis
Uses(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholinocarbenium hexafluorophosphate is used as a coupling reagent in the peptide synthesis. It is suitable for solution phase & solid phase peptide synthesis, visual or colorimetric reaction monitoring possible.
UsesCOMU – Safer and More Efficient Peptide Coupling ReagentAdvantages
  • Equal or even superior performance to HATU
  • Non-explosive (does not contain benzotriazole moiety)
  • Suitable for solution phase & solid phase peptide synthesis
  • Utmost retention of configuration – low to non-existent racemization
  • High solubility and stability in typical solvents
  • Visual or colorimetric reaction monitoring possible
  • Easy removal of water-soluble by-products
General DescriptionThis product is a Safer, non-explosive and more effective replacement for Benzotriazole-Based peptide coupling reagents and thus aligns with "Less Hazardous Chemical Synthesis" and "Inherently Safer Chemistry for Accident Prevention".
COMU Preparation Products And Raw materials

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