Product

EPINASTINE HYDROCHLORIDE

CAS No.：108929-04-0

Other grades of this product :

EPINASTINE HYDROCHLORIDE Basic information

Product Name:	EPINASTINE HYDROCHLORIDE
Synonyms:	f)imidazo(1,5-a)azepin-3-amine,9,13b-dihydro-ih-dibenz(hydrochloride;EPINASTINE HCL;EPINASTIN HCL;3-AMINO-9,13B-DIHYDRO-1H-DIBENZ[C,F]IMIDAZO[1,5-A]AZEPINE HYDROCHLORIDE;WAL-801CL;9,13b-Dihydro-1H-Dibenz[c,f]imidazo[1,5-α]azepin-3-amine Hydrochloride;Alesion;Elestat
CAS:	108929-04-0
MF:	C16H16ClN3
MW:	285.77
EINECS:	629-843-8
Product Categories:	Inhibitors;Heterocyclic Compounds;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Antihistaminic;Pharmaceuticals
Mol File:	108929-04-0.mol

EPINASTINE HYDROCHLORIDE Chemical Properties

Melting point	273-275°C
storage temp.	2-8°C
solubility	H2O: soluble38mg/mL
form	solid
color	white
InChIKey	VKXSGUIOOQPGAF-UHFFFAOYSA-N

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	HO4360000
HS Code	2933992600
Toxicity	LD50 in male, female rats (mg/kg): 314, 192 orally; 17, 22 i.v. (Nishikawa)

MSDS Information

EPINASTINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	A tetracyclic, non-sedating histamine H1 receptor antagonist. Antihistaminic.
Biochem/physiol Actions	Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist.

EPINASTINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

11H-Dibenz[b,e]azepine, 6-chloro--->6-Aminomethyl-5,6-dihydromorphanthridine-->N-[2-(Phenylmethyl)phenyl]-2-chloroacetamide-->11H-Dibenzo[b,e]azepine-6-carbonitrile-->Epinastine-->2-Benzylaniline-->Cyanogen bromide-->2-Aminobenzophenone

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