lactosyl lysosphingolipid

lactosyl lysosphingolipid
  • CAS No.:109785-20-8
Other grades of this product :
lactosyl lysosphingolipid Basic information
Product Name:lactosyl lysosphingolipid
Synonyms:2-[6-[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;Lactosylsphingosine (d18:1);Lyso-Lactosylceramide (synthetic);Lactosyl-C18-sphingosine;lactosyl lysosphingolipid;D-lactosyl-1-1'-D-erythro-sphingosine;Lactosylsphingosine (d18:1) (synthetic);Lactosyl(ss) Sphingosine (d18:1)
CAS:109785-20-8
MF:C30H57NO12
MW:623.77308
EINECS:
Product Categories:
Mol File:109785-20-8.mol
lactosyl lysosphingolipid Chemical Properties
storage temp. -20°C
BRN 5680460
Safety Information
MSDS Information
lactosyl lysosphingolipid Usage And Synthesis
DescriptionLactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3. [Matreya, LLC. Catalog No. 2088]
UsesLactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column.
General DescriptionLactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract.
Biochem/physiol ActionsLactosyl sphingosine?exhibits better hemolytic activity than lysolecithin.
lactosyl lysosphingolipid Preparation Products And Raw materials

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