PAROXETINE-D4 HCL

PAROXETINE-D4 HCL
  • CAS No.:110429-35-1
Other grades of this product :
PAROXETINE-D4 HCL Basic information
Product Name:PAROXETINE-D4 HCL
Synonyms:Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S,4R)- (9CI);1,3-benzodioxol-5-yl-[4-(4-fluorophenyl)-3-piperidinyl]methanol hydrochloride;PAROXETINE-D4 HCL kf-yuwen(at)kf-chem.com;Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S-trans)-;Paroxetine Hydrochloride (350 mg);Paroxetine Hydrochloride (350 mg)G0D0030.972mg/mg(ai);Paroxetine-D4 hydrochloride;PAROXETINE-D4 HCL
CAS:110429-35-1
MF:C19H23ClFNO4
MW:383.84
EINECS:000-000-0
Product Categories:Active Pharmaceutical Ingredients;Cnbio;Serotonin
Mol File:110429-35-1.mol
PAROXETINE-D4 HCL Chemical Properties
Melting point 121-131 C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol (96 per cent) and in methylene chloride.
form powder
color white
λmax292nm(H2O)(lit.)
Merck 14,7043
CAS DataBase Reference110429-35-1
Safety Information
Hazard Codes F,C,Xn
Risk Statements 11-34-36/37/38-22
Safety Statements 16-26-36/37/39-45-36
RIDADR UN 3077 9 / PGIII
WGK Germany 3
RTECS TM4569320
HazardClass IRRITANT
HS Code 29349990
MSDS Information
PAROXETINE-D4 HCL Usage And Synthesis
Chemical PropertiesWhite or almost white, crystalline powder.
UsesParoxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).
UsesAntidepressant;5-HT uptake inhibitor
UsesParoxetine hydrochloride hemihydrate has been used: as an antidepressant to study its effects on neural stem cells (NSCs) from embryonic rat hippocampus in vitro; as a CYP 2D6 inhibitor to study its effects on the in vitro?production by human recombinant CYP 2D6 of the phenolic metabolites; as an antidepressant to study its effects on the expression of pituitary adenylate cyclase activating polypeptide (PACAP), its receptors and brain-derived neurotrophic factor (BDNF) in rat primary hippocampal neurons
General DescriptionPharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Biochem/physiol ActionsParoxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant
PAROXETINE-D4 HCL Preparation Products And Raw materials
Raw materials1-Piperidinecarboxylic acid, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, 1,1-dimethylethyl ester, (3S,4R)-
Preparation ProductsParoxetine

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