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| 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Basic information |
| Product Name: | 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione | | Synonyms: | 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione;BYK 204165;4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione;PARP Inhibitor XIV;4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione;RT-017290;1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-;BYK204165 >=98% (HPLC) | | CAS: | 1104546-89-5 | | MF: | C15H12N2O2 | | MW: | 252.27 | | EINECS: | | Product Categories: | | Mol File: | 1104546-89-5.mol |
| 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Chemical Properties |
| Boiling point | 492.5±45.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >20mg/mL | | pka | 9.30±0.20(Predicted) | | form | powder | | color | yellow |
| Hazard Codes | Xi | | Risk Statements | 43 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Usage And Synthesis |
| Uses | BYK 204165 is an inhibitor of the poly(ADP-?ribose) polymerase (PARP), and it is 100-fold more selective for PARP-1. | | Biochem/physiol Actions | BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2. |
| 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Preparation Products And Raw materials |
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![4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione](/img/1104546-89-5.jpg "4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione")
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