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| XTT sodium salt Basic information |
| Product Name: | XTT sodium salt | | Synonyms: | XTT sodium salt;2,3-Bis(2-methoxy-4-nitro-5-sulphophenyl)-2H-tetrazolium-5-carboxanilide inner salt;SODIUM 3,3'-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]BIS (4-METHOXY-6-NITRO)BENZENE SULFONIC ACID HYDRATE;SODIUM-3,3-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]-BIS(4-METHOXY-6-NITRO)BENZENE SULPHONIC ACID HYDRATE;XTT;xttsodium;XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide);XTT SODIUM CELL CULTURE TESTED | | CAS: | 111072-31-2 | | MF: | C22H18N7NaO13S2 | | MW: | 675.53 | | EINECS: | 601-039-1 | | Product Categories: | reagent;Tetrazolium salt | | Mol File: | 111072-31-2.mol |
| XTT sodium salt Chemical Properties |
| Melting point | 285 ℃ (decompose) | | storage temp. | 2-8°C | | solubility | hot water: 2.5 mg/mL | | form | powder | | color | Yellow | | Water Solubility | Soluble in hot water at 2.5mg/ml.Soluble in water, dimethyl sulfoxide, dimethyl formamide and phosphate buffered saline.at pH =7.2. | | λmax | 286 nm | | Biological Applications | Cell proliferation assays; cytotoxicity assays; ecotoxicity assays; neurotoxicity assays; antimicrobial susceptibility testing assays; antifungal susceptibility testing assays; cardiac valve viability assays; cell viability assay | | CAS DataBase Reference | 111072-31-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HS Code | 29339900 |
| XTT sodium salt Usage And Synthesis |
| Uses | Tetrazolium derivative useful in cancer research.XTT sodium salt is used in conjunction with phenazine methosulfate to screen human cancer cell lines. It is also used to study fungal cell damage. It is involved in testing antimicrobial susceptibility of staphylococci and in candida biofilm research. Further, it is used in an assay for cell viability and cell proliferation. | | Uses | Useful in AIDS and cancer testing. | | General Description | XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is a tetrazolium salt, which forms water-soluble formazan on bioreduction. | | Biochem/physiol Actions | XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is acted upon by dehydrogenases present in metabolically active cells. This produces water soluble formazan, which is a highly colored product. Thus, it offers an advantage in colorimetric proliferation assays, as opposed to MTT, as the product is already soluble and no formazan crystals are formed. |
| XTT sodium salt Preparation Products And Raw materials |
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