tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

CAS No.：112741-49-8

Other grades of this product :

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Basic information

Product Name:	tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Synonyms:	CIVENTICHEM CV-2653;CIVENTICHEM CV-2654;TERT-BUTYL (2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE;N-TERT-BUTOXYCARBONYL-(2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE;N-BOC(2R, 3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE CARBOXYLATE;tert-butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morph;TERT-BUTYL (2R,3S)-(-)-6-OXO-2,3-DIPHENY L-4-MORPHOLINECARBOXYLATE, 99% (99% EE);(2R,3S)-6-Oxo-2,3-diphenyl-morpholine-4-carboxylic acid tert-butyl ester
CAS:	112741-49-8
MF:	C21H23NO4
MW:	353.41
EINECS:
Product Categories:	API intermediates;Chiral Building Blocks;Heterocyclic Building Blocks;Morpholines
Mol File:	112741-49-8.mol

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties

Melting point	206 °C (dec.)(lit.)
alpha	-87 º (c=5.5 in methylene chloride)
Boiling point	509.6±50.0 °C(Predicted)
density	1.175±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Acetone (Slightly, Heated, Sonicated), Chloroform (Slightly), DMSO (Slightly, So
form	Solid
pka	-3.28±0.60(Predicted)
color	White to Off-White
optical activity	[α]25/D 87°, c = 5.5 in methylene chloride
InChIKey	MRUKRSQUUNYOFK-RBUKOAKNSA-N

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
HS Code	2934999090

MSDS Information

Provider	Language
SigmaAldrich	English

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Usage And Synthesis

Chemical Properties	tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is Off-white Solid
Uses	Tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and colla gen cross-link pyridinolines.
Uses	(2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and collagen cross-link pyridinolines.

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials

Preparation Products

(S)-N-Boc-allylglycine

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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