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| 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT Basic information |
| Product Name: | 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT | | Synonyms: | 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT;2'-3'-O-(4-benzoylbenzoyl)adenosine*5'-triphospha;2'-3'-O-(4-BENZOYLBENZOYL)ADENOSINE5'-TR IPHOSPHATE;BENZOYLBENZOIC ADENOSINE 5'-TRIPHOSPHATE;2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphatetri(triethylammonium)salt;BzATP triethylammonium salt;2'(3')-o-(4-benzoylbenzoyl)adeno;Adenosine 5'-(tetrahydrogen triphosphate) 3'-(4-benzoylbenzoate) compd. with N,N-diethylethanamine | | CAS: | 112898-15-4 | | MF: | C30H39N6O15P3 | | MW: | 816.58 | | EINECS: | | Product Categories: | | Mol File: | 112898-15-4.mol |
| 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT Chemical Properties |
| storage temp. | -20°C | | solubility | ≤14 mg/ml in DMSO | | form | solid | | color | white to off-white | | InChIKey | HVOVBTNCGADRTH-WBLDMZOZSA-N |
| 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT Usage And Synthesis |
| Uses | 2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate triethylammonium salt has been used as a P2X4 receptor agonist in rat kidney sections, type I diabetes induced rats and astrocyte?neuron coculture. It has also been used as a synthetic ATP analog in isotonic E3 medium. | | General Description | 2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate is a photoreactive analog of ATP. | | Biological Activity | Prototypic P2X 7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP (EC 50 = 0.7 μ M in HEK 293 cells). Exhibits partial agonist activity at P2X 1 (pEC 50 = 8.7) and P2Y 1 receptors and can be used as a photoaffinity label for ATPase. | | Biochem/physiol Actions | 2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate triethylammonium salt is a selective purinergic receptor (P2X) agonist. It is more potent than ATP at homodimeric P2X7 receptors. It also effectively activates P2X1, P2X2, and P2X3 receptors. Useful as a photoaffinity label for proteins and enzymes that bind ATP. |
| 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT Preparation Products And Raw materials |
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