Product

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride

CAS No.：1177141-67-1

Other grades of this product :

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Basic information

Product Name:	N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
Synonyms:	CKI-7 Dihydrochloride;N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride;CKI-7 dihydrochlorid;N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride;CKI-7 2HCL
CAS:	1177141-67-1
MF:	C11H14Cl3N3O2S
MW:	358.67176
EINECS:
Product Categories:	Inhibitors;Protein Kinase Inhibitors and Activators;All Inhibitors
Mol File:	1177141-67-1.mol

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Chemical Properties

Melting point	187-189°C
storage temp.	-20°C
solubility	H2O: >5mg/mL
form	solid
color	white to light tan

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

MSDS Information

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Usage And Synthesis

Chemical Properties	Beige Solid
Uses	Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases
Biochem/physiol Actions	CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Preparation Products And Raw materials

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