Other grades of this product :
| Product Name: | PAz-PC | | Synonyms: | 1-PALMITOYL-2-AZELAOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;PAZPC;16:0-09:0 (ALDO) PC;1-PALMITOYL-2-(9'-OXO-NONANOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0-09:0 (ALDO) PC;PazePC | | CAS: | 117746-89-1 | | MF: | C33H64NO10P | | MW: | 665.835721 | | EINECS: | | Product Categories: | | Mol File: | 117746-89-1.mol |
| PAz-PC Chemical Properties |
| storage temp. | -20°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White Sticky | | Stability: | Hygroscopic |
| PAz-PC Usage And Synthesis |
| Uses | PazePC is an oxidatively modified phospholipid that modulates reactions between Bax (a pro-apoptotic protein) and mitochondrial membranes under intracellular oxidative stress, often resulting in cell death. PazePC is found in low density cholesterol (LDL). | | General Description | 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) structure contains an anionic carboxyl group at the end of the short, oxidized acyl chain. | | Biochem/physiol Actions | 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) is an oxidized lipid. PAzePC acts as an inter- H2O2 permeation promoter. It serves as a drug target for antipsychotic drugs and antimicrobial agents in cells under oxidative stress at inflammatory sites. PAzePC facilitates permeabilization of Bax associated-mitochondrial membranes under oxidative stress. |
| PAz-PC Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye