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| (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid Basic information |
| Product Name: | (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid | | Synonyms: | (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid;5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid;PS 48;(Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid;PS 48;PS-48;PS-48;PS 48;PS48;CS-1466;2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)- | | CAS: | 1180676-32-7 | | MF: | C17H15ClO2 | | MW: | 286.75 | | EINECS: | | Product Categories: | | Mol File: | 1180676-32-7.mol |
| (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid Chemical Properties |
| Melting point | 114-115℃ | | Boiling point | 444.1±24.0 °C(Predicted) | | density | 1.225±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >20mg/mL | | form | powder | | pka | 4.55±0.10(Predicted) | | color | white to off-white |
| (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid Usage And Synthesis |
| Uses | PS 48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator. | | Biochem/physiol Actions | PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site. |
| (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid Preparation Products And Raw materials |
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