Other grades of this product :
| Product Name: | CLP257 | | Synonyms: | (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone;CLP257;4(5H)-Thiazolone, 5-[(4-fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1(2H)-pyridazinyl)-, (5Z)- | | CAS: | 1181081-71-9 | | MF: | C14H14FN3O2S | | MW: | 307.34 | | EINECS: | | Product Categories: | | Mol File: | 1181081-71-9.mol |
| CLP257 Chemical Properties |
| Boiling point | 473.3±55.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | form | powder | | pka | 7.23±0.40(Predicted) | | color | white to yellow to light brown |
| CLP257 Usage And Synthesis |
| Uses | CLP257 has been used as a K+- Cl- cotransporter 2 (KCC2) enhancer in human neuron culture. | | Biochem/physiol Actions | CLP257 is a selective K+-Cl? cotransporter KCC2 activator that restored impaired Cl? transport in neurons with reduced KCC2 activity. Apparently, CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally. |
| CLP257 Preparation Products And Raw materials |
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